Recombinant Human/Murine/Rat BDNF protein (Active) ab9794 from Abcam

Product Specs
ItemRecombinant Human/Murine/Rat BDNF protein (Active)
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab9794
Size10 µg
NCBI Gene AliasesANON2, BULN2
Gene NameBDNF
Source/Expression SystemEscherichia coli
ActivityActive
Molecule NameBDNF
TypeProteins
NCBI Full Gene Namebrain derived neurotrophic factor
Research AreaNeuroscience
ApplicationsCellAct, FuncS, HPLC, SDS-PAGE, WB
FormatSterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg)

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Mechanical acupuncture at HT7 attenuates alcohol self-administration in rats by modulating neuroinflammation and altering mPFC-habenula-VTA circuit activityFrontiers in Behavioral NeuroscienceOctober 30, 2024Su Yeon Seo, Se Kyun Bang, Suk Yun Kang, Seong Jin Cho, Kwang-Ho Choi, Yeonhee Ryumicroinjection include Simga 1 receptor antagonist; BD1047 (#0956, Tocris Bioscience, Bristol, UK), BDNF (#ab9794, Abcam, Cambridge, MA, USA) and microglia inhibitor; This is Minocycline (#3268, Tocris Bioscience).

(2) High Intensity Acute Aerobic Exercise Elicits Alterations in Circulating and Skeletal Muscle Tissue Expression of Neuroprotective ExerkinesBrain PlasticityOctober 21, 2022Corey E. Mazo, Edwin R. Miranda, James Shadiow, Michael Vesia, Jacob M. Hausbanding patterns were confirmed using human recombinant CTSB (ab283434, Abcam, Cambridge, UK) or BDNF (ab9794 Abcam, Cambridge, UK) protein as shown in Figs. 3A and 4A, respectively. For CTSB, bands were identical

(3) High-Contrast Stimulation Potentiates the Neurotrophic Properties of Müller Cells and Suppresses Their Pro-Inflammatory PhenotypeInternational journal of molecular sciencesAugust 3, 2022Zloh M, Kutilek P, Stofkova A.potential of MCs (Figure S5). After 1 day of adhesion, cells were treated with recombinant BDNF protein (ab9794, Abcam, Cambridge, UK) at three different concentrations (0.1 nM, 1 nM, and 10 nM) for 48 h and were

(4) Brain-Derived Neurotrophic Factor Secreting Human Mesenchymal Stem Cells Improve Outcomes in Rett Syndrome Mouse ModelsFrontiers in NeuroscienceOctober 6, 2021Hyo Jeong Kim, Delger Bayarsaikhan, Jaesuk Lee, Govigerel Bayarsaikhan, Bonghee Leelateral: 1.0 mm, dorsal: 3.0 mm from Bregma). For protein injection, 500 ng of BDNF protein (Abcam, ab9794) was prepared in 10 μL of saline. For the UCB-MSC injection, 5 × 105 cells were prepared in 10 μl of

(5) Three-Dimensional Model of Dorsal Root Ganglion Explant as a Method of Studying Neurotrophic Factors in Regenerative MedicineBiomedicinesMarch 3, 2020Polina Klimovich, Kseniya Rubina, Veronika Sysoeva, Ekaterina SeminaCat# 15240–096). Mouse NGF (100 ng/mL; Sigma-Aldrich, Cat# SRP4304), mouse BDNF (50 ng/mL; Abcam, Cat# ab9794), and mouse GDNF (50 ng/mL; Abcam, Cat# ab56286) or 10% bovine serum albumin (BSA), lyophilized powder,

(6) Exogenous brain-derived neurotrophic factor attenuates neuronal apoptosis and neurological deficits after subarachnoid hemorrhage in ratsExperimental and therapeutic medicineNovember 1, 2019Chen H, Dang Y, Liu X, Ren J, Wang H.bregma). The rats received ICV injection of recombinant rat BDNF protein (10 µl, 0.5 nmol; cat. no. Ab9794; Abcam) or vehicle (10 µl PBS) at 30 min after SAH. After injection, the needle was kept for 5 min and

(7) mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTORFrontiers in cellular neuroscienceJanuary 1, 2019Sanders SS, De Simone FI, Thomas GM.mM KCl, 2 mM CaCl2, 20 mM glucose, 1 mM MgCl2] for 2 h prior to the addition of 100 ng/mL of BDNF (#ab9794, Abcam, Cambridge, United Kingdom, stock solution was 100 μg/mL) or 5 mM Leucine (MP Biomedicals, Santa

(8) Dexmedetomidine attenuates the toxicity of β‑amyloid on neurons and astrocytes by increasing BDNF production under the regulation of HDAC2 and HDAC5Molecular Medicine ReportsNovember 26, 2018Yueling Wang, Aijun Jia, Wenjuan Ma2019 simultaneously treated with Aß and Dex (Sigma‑Aldrich; Merck KGaA), Recombinant Human/Murine/Rat BDNF protein (ab9794) or Trichostatin A (ab120850; both Abcam, Cambridge, UK), a selective inhibitor of HDACs for 24 h. MTT assay

(9) Design of a Novel Gene Therapy Construct to Achieve Sustained Brain-Derived Neurotrophic Factor Signaling in NeuronsHuman Gene TherapyJuly 1, 2018Andrew Osborne, Aiden X.Z. Wang, Alessia Tassoni, Peter S. Widdowson, Keith R. Martinconfluent. The medium was then exchanged for 100 μL of DMEM (no additives) containing mBDNF (cat. #ab9794; Abcam, Cambridge, United Kingdom) at concentrations between 25 and 200 ng/mL, or 100 μL of transduced

(10) Silver nanoparticles suppresses brain-derived neurotrophic factor-induced cell survival in the human neuroblastoma cell line SH-SY5YJournal of Industrial and Engineering ChemistryNovember 13, 2016Jung Hyun Park, Sangiliyandi Gurunathan, Yun-Jung Choi, Jae Woong Han, Hyuk Song, Jin-Hoi Kim

(11) Brain-Derived Neurotrophic Factor Ameliorates Learning Deficits in a Rat Model of Alzheimer's Disease Induced by Aβ1-42PLOS ONEApril 7, 2015Lu Zhang et al.concentration of 5 mg/ml and incubated at 37°C for 72 h to induce aggregation. Human full length BDNF (ab9794), NGF (ab138794) and NT-3 (ab138798) proteins and their corresponding rabbit polyclonal antibodies (ab75040,

(12) The Brain-Uterus Connection: Brain Derived Neurotrophic Factor (BDNF) and Its Receptor (Ntrk2) Are Conserved in the Mammalian UterusPLoS ONEApril 8, 2014Jocelyn M. Wessels, Liang Wu, Nicholas A. Leyland, Hongmei Wang, Warren G. Fostercontrol), 2) anti-BDNF or anti-Ntrk2 pre-incubated with an excess of human recombinant protein (BDNF Abcam ab9794 and Ntrk2 Abcam ab56652) at a 5:1 ratio with the antibody, or 3) normal goat serum in lieu of primary

(13) Sexual dimorphism in BDNF signaling after neonatal hypoxia-ischemia and treatment with necrostatin-1NeuroscienceFebruary 28, 2014Chavez-Valdez R, Martin LJ, Razdan S, Gauda EB, Northington FJ.β-actin. NIH-PA Author Manuscript 2.6. Positive controls and antibodies Positive controls—Mature BDNF (ab9794; Abcam Inc, Cambridge, MA): 0.1 μg of human recombinant showing a band at 14 kDa. TrkB (sc-113925; Santa Cruz Biotechnology, Inc

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Recombinant Human/Murine/Rat BDNF protein (Active) from Abcam

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Recombinant Human/Murine/Rat BDNF protein (Active) from Abcam

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