AGE-BSA ab51995 from Abcam

Product Specs
ItemAGE-BSA
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab51995
FormatPurity > 98% 0.22 µm filter sterilized
Size10 mg
Concentration10 mg/ml
ApplicationsSDS-PAGE
Source/Expression SystemNative
ActivityInactive
SpeciesCow
Molecule NameAGE
TypeProteins

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(1) Enalaprilat reverses neutrophil polarization imbalance via targeting taurine-STING axis for treatment of diabetic woundsCell Reports MedicineApril 21, 2026Li Lu, Yuan Xiong, Jiewen Liao, Juan Zhou, Guangji Wang, Yating Qin, Shengming Zhang, Yanzhi Zhao, Xiaodan Zhong, Mengwen Wang, et al.peptides, and recombinant proteins" ,, Alginate methacryloyl,Engineering for Life,N/A AGE-BSA,Abcam,Cat#ab51995 cFLFLFK-NH2 peptide,BioAct Peptide Biotech,N/A Enalaprilat,MedChemExpress,Cat#HY-B0231 Erastin,MedChemExpress,Cat#HY-15763 Ferrostatin-1,MedChemExpress,Cat#HY-100579 H-151,MedChemExpress,Cat#HY-112693 Lipofectamine 3000

(2) Baicalin ameliorates podocyte injury and renal function impairment in idiopathic membranous nephropathy by inhibiting the AGE/RAGE signalingRen FailApril 20, 2026Chengli Lou, Yijing Zhou, Bo Feng, Xiaoping Fan, Xiuqin Xu, Pingxin Hu, Xiangjing Wanga mixture of BAI-L and 200 μg/mL advanced glycation end products - bovine serum albumin (AGE-BSA) (ab51995, Abcam, Cambridge, UK) for 24 h. Network pharmacology investigation First, we conducted target prediction

(3) Inhibitory Mechanism of Buyang Huanwu Decoction on AGE/RAGE Pathway in Membranous Nephropathy: Integration of Network Pharmacology and Cell Model ValidationInternational Journal of General MedicineJanuary 17, 2026Lin Fu, Nenghua Zhang, Xingying Chen, Xiuqin Xu, Yunqiu Shen+ BYHWD-H + AGE-BSA group (10% ZAS + 10 mg/mL BYHWD + 200 μg/mL AGE-BSA, AGE/RAGE pathway agonist, ab51995, Abcam, Cambridge, UK, 24 h). In addition, the conditionally immortalized human podocyte cell line AB8/13,

(4) SIRT3 attenuates AGEs-induced senescence in human granulosa cells through enhancing mitophagyCell Biology and ToxicologyJanuary 13, 2026Shuhang Li, Mingge Tang, Sihui Zhu, Zhiguo Zhang, Yunxia Cao, Rufeng Xueprocesses behind ovarian aging. Materials and methods Materials AGEs solution was purchased from Abcam (ab51995, USA). Urolithin A (UA, HY-100599) and cyclosporine A (CsA, HY-B0579) were purchased from MedChemExpress

(5) Mechanisms of AGE-induced VSMC phenotypic switching and macrophage modulation in human abdominal aortic aneurysmsExp Biol Med (Maywood)August 7, 2025Xiaoying Ma, Jinfang Xu, Huiying Sun, Jiajun Liu, Shibo Xia, Hao Zhang, Chaoyi Cui, Chao SongLLCNJ, United states. Advanced glycation end product-BSA (AGE-BSA) was purchased from Abcam (Cat. No. ab51995, Abcam, Cambridge, United kingdom). Real-time quantitative reverse transcription-polymerase chain reaction

(6) GlmS plays a key role in the virulence factor expression and biofilm formation ability of Staphylococcus aureus promoted by advanced glycation end productsVirulenceDecember 31, 2024Lijia Ni, Rui Shen, Hua Luo, Xuexue Li, Xiaofan Zhang, Lisi Huang, Yawen Deng, Xiaoyan Liao, Yonglin Wu, Chaohui Duan, et al.stimulated with 50 µg/mL AGEs in TSB broth and cultured for 24 h. AGEs were purchased from Abcam, USA (ab51995). The blank groups were stimulated with the same concentration of bovine serum albumin (BSA) (EZ7890B203,

(7) AGEs impair osteogenesis in orthodontic force-induced periodontal ligament stem cells through the KDM6B/Wnt self-reinforcing loopStem Cell Research & TherapyNovember 15, 2024Qiaohui Ying, Yujun Jiang, Changyun Sun, Yaoguang Zhang, Ruihan Gao, Hongrui Liu, Hongrui Liu, Jie Guo, Minqi Liof AGEs/RAGE on mechanically induced osteogenesis was assessed by introducing exogenous AGEs (Abcam, ab51995) at 200 µg/ml and FPS-ZM1 (MCE, HY-19370) at 10 µM. The role of KDM6B was inhibited with 5 µM GSK-J4

(8) Deficiency of Nuclear Receptor Coactivator 3 Aggravates Diabetic Kidney Disease by Impairing Podocyte AutophagyAdvanced ScienceMay 1, 2024Yaru Xie, Qian Yuan, Xinyi Cao, Yang Qiu, Jieyu Zeng, Yiling Cao, Yajuan Xie, Xianfang Meng, Kun Huang, Fan Yi, et al.the osmotic pressure control for HG; (2) advanced glycation end products (AGE, 50, 100, 150 µg mL−1, ab51995, Abcam, Cambridge, UK). RNA Extraction and Reverse Transcription‐Quantitative PCR (RT‐qPCR) RT‐qPCR

(9) Advanced Glycation End Products Downregulate Connexin 43 and Connexin 40 in Diabetic Atrial Myocytes via the AMPK PathwayDiabetes, Metabolic Syndrome and ObesityOctober 2, 2023Fan Yang, Huan-Huan Liu, Lei Zhang, Xiao-Lu Zhang, Jie Zhang, Feng Li, Ning Zhao, Zhi-Yuan Zhang, Qi Kong, Xiao-Yu Liu, et al.effect AGEs on Cx43 and Cx40 expression, primary atrial myocytes were exposed to 100 μg/mL AGEs-BSA (ab51995, Abcam) for 24 hours. Cells cultured with 100 μg/mL non-glycated BSA (A3803, Sigma) were used as a control. HL-1

(10) Advanced glycation end products impair coronary artery BK channels via AMPK/Akt/FBXO32 signaling pathwayDiabetes and Vascular Disease ResearchAugust 18, 2023Xiao-Yan Li, Ling-Ling Qian, Ying Wu, Yu-Min Zhang, Shi-Peng Dang, Xiao-Yu Liu, Xu Tang, Cun-yu Lu, Ru-Xing Wanghuman coronary arterial SMCs were exposed to 100 μg/mL AGEs-bovine serum albumin (AGEs-BSA) (Abcam, #ab51995) for 48 h. Cells cultured with 100 μg/mL non-glycated BSA were used as a BSA control. 11 To further

(11) Increased dietary intake of ultraprocessed foods and mitochondrial metabolism alterations in pediatric obesitySci RepAugust 3, 2023Serena Coppola, Lorella Paparo, Giovanna Trinchese, Andrea Margarita Rivieri, Antonio Masino, Anna Fiorenza De Giovanni Di Santa Severina, Mariapina Cerulo, Maria Escolino, Assunta Turco, Ciro Esposito, et al.protocol PBMCs (3.5 × 105cells/well) from healthy children were stimulated with 200 µg/mL of AGE-BSA (#ab51995, Abcam, Cambridge, UK; purity: > 98%; endotoxin level: < 0.100 Eu/µg) or BSA (Sigma-Aldrich, Missouri,

(12) Galectin‐3 and RAGE differentially control advanced glycation endproduct‐induced collagen damage in murine intervertebral disc organ cultureJOR SPINEJune 1, 2023Zachary S. Gallate, Danielle N. D'Erminio, Philip Nasser, Damien M. Laudier, James C. Iatridisidentical with the control media except for the replacement of 20 μg/mL BSA with 20 μg/mL AGE‐BSA (ab51995; Abcam). 2.2 Cell viability, collagen damage, degeneration grading, and Immunohistochemistry Following

(13) Resveratrol Alleviates Diabetic Periodontitis-Induced Alveolar Osteocyte Ferroptosis Possibly via Regulation of SLC7A11/GPX4NutrientsApril 28, 2023Yue Li, Zhijun Huang, Shuaifei Pan, Yuhui Feng, Haokun He, Shuguang Cheng, Lijing Wang, Liping Wang, Janak Lal Pathakfrequently used to mimic the inflammatory condition of periodontitis in vitro [36]. AGEs (200 μg/mL) (Abcam, ab51995, Cambridge, UK) and LPS (1, 2, or 4 μg/mL) (InvivoGen, San Diego, CA, USA) were added to the MLOY4 cell culture

(14) Treatment with quercetin inhibits SARS-CoV-2 N protein-induced acute kidney injury by blocking Smad3-dependent G1 cell-cycle arrestMolecular therapy : the journal of the American Society of Gene TherapyFebruary 1, 2023Wu W, Wang W, Liang L, Chen J, Wei B, Huang XR, Wang X, Yu X, Lan HY.streptomycin (Gibco, Thermo Fisher Scientific). Cells were stimulated with or without AGE (50 μg/mL; ab51995; Abcam) for different time points. HEK293T cells were cultured in DMEM supplemented with 10% FBS, 100

(15) SARS-CoV-2 N protein induced acute kidney injury in diabetic db/db mice is associated with a Mincle-dependent M1 macrophage activationFrontiers in immunologyJanuary 1, 2023Wu W, Wang W, Liang L, Chen J, Sun S, Wei B, Zhong Y, Huang XR, Liu J, Wang X, et al.ThermoFisher). Cells were stimulated with or without advanced glycation end products (AGE, 100μg/ml, ab51995, Abcam), a hyperglycemia-related products associated with the development of diabetic kidney disease

(16) Advanced glycation end products induce senescence of atrial myocytes and increase susceptibility of atrial fibrillation in diabetic miceAging CellDecember 1, 2022Dan‐Lin Zheng, Qing‐Rui Wu, Peng Zeng, Sui‐Min Li, Yong‐Jiang Cai, Shu‐Zhen Chen, Xue‐Shan Luo, Su‐Juan Kuang, Fang Rao, Ying‐Yu Lai, et al.ab189034); rabbit polyclonal to Rb (1:1000; ab226979; Abcam, UK); rabbit polyclonal to AGE (1:1000; ab51995; Abcam, UK); rabbit polyclonal to RAGE (1:1000; ab65965; Abcam, UK). The signals were normalized to

(17) Tribbles Homolog 3 Mediates the Development and Progression of Diabetic RetinopathyDiabetesAugust 1, 2021Pitale PM, Saltykova IV, Adu-Agyeiwaah Y, Calzi SL, Satoh T, Akira S, Gorbatyuk O, Boulton ME, Pardue MT, Garvey WT, et al.H-1200-10 Mm00454879_m1 Mm00479862_g1 Mm03294838_g1 Mm00516023_m1 Mm00468869_m1 Mm00441480_m1 Mm00476361_m1 Mm01284492_m1 Mm00437304_m1 Mm00462533_m1 Mm99999915_g1 Mm00446953_m1 Origene- Product number MR204806 XIP (Prof Limb) Abcam# ab51995 Thermo Scientific™ AN0010W Sigma-Aldrich# M5655 Thermofisher Scientific Assay ID# 42840 Thermofisher

(18) CUPRAC-Reactive Advanced Glycation End Products as Prognostic Markers of Human Acute Myocardial InfarctionAntioxidants (Basel)March 11, 2021Govigerel Bayarsaikhan, Delger Bayarsaikhan, Pyung Chun Oh, Woong Chol Kang, Bonghee Lee(Gyeonggi, Republic of Korea) and MP Biomedical (Irvine, CA, USA). The commercial standard for AGE-BSA (ab51995) was obtained from Abcam (Cambridge, UK). The Pierce BCA Protein Assay Kit (cat. no. 23215) was obtained

(19) Advanced glycation end products cause RAGE ‐dependent annulus fibrosus collagen disruption and loss identified using in situ second harmonic generation imaging in mice intervertebral disk in vivo and in organ culture modelsJOR SPINEDecember 1, 2020Robert C. Hoy, Danielle N. D'Erminio, Divya Krishnamoorthy, Devorah M. Natelson, Damien M. Laudier, Svenja Illien‐Jünger, James C. Iatridisseparated into a control group and the remaining two were placed in the AGE‐bovine serum albumin (AGE‐BSA; ab51995; Abcam) group. Each level was placed in a 24 well plate, and cultured for 10 days in control or AGE‐BSA

(20) Circulating Ligands of the Receptor for Advanced Glycation End Products and the Soluble Form of the Receptor Modulate Cardiovascular Cell Apoptosis in DiabetesMolecules (Basel, Switzerland)November 10, 2020Tsoporis JN, Hatziagelaki E, Gupta S, Izhar S, Salpeas V, Tsiavou A, Rigopoulos AG, Triantafyllis AS, Marshall JC, Parker TG, et al.PRO-601, Prospec Protein Specialists, East Brunswick, NJ, USA), high glucose (4.5 g/L), AGEs (50 µg/mL; ab51995, Abcam, Cambridge, MA, USA), S100B (100 pg/mL; 1820-SA-050, R&D Biosystems, Minneapolis, MN, USA), S100A1 (10

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AGE-BSA from Abcam

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AGE-BSA from Abcam

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