TOPBP1 ELISA kits are immunoassay tools for the measurement of the protein DNA topoisomerase II binding protein 1, which is encoded by the TOPBP1 gene in humans. Functionally, this protein is known to be required for DNA replication. The canonical protein structure is reported to have an amino acid sequence of 1522 residues and a mass of 170.7 kDa. It is known to be localized in the nucleus and cytoplasm and is reported to be highly expressed in heart, brain, placenta, lung and kidney. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. Other alias names for this target include TOP2BP1, DNA topoisomerase 2-binding protein 1, DNA topoisomerase II-beta-binding protein 1, topoisomerase (DNA) II binding protein 1, and Dpb11.
Some TopBP1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.