The AAT ELISA kits listed below utilize specific antibodies for the plate-based assay of AAT in various samples. AAT is another term for the SERPINA1 gene, which encodes the protein, serpin family A member 1 in humans. The target protein is known as an inhibitor of serine proteases. Structurally, the SERPINA1 protein is 418 amino acid residues in length and 46.7 kilodaltons in mass. However, as many as 3 protein isoforms have been identified. Its subcellular localization is in the ER, extracellular matrix, and is secreted. In terms of tissue specificity, it is ubiquitously expressed across many tissue types. This protein is known to be N-glycosylated and cleaved. Other names for this target antigen include A1A and A1AT.
Some AAT ELISA kits can detect targets at levels as low as 1.56 ng/mL and as high as 2000 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.