RPN2 ELISA kits are immunoassay tools for the measurement of the protein ribophorin II, which is encoded by the RPN2 gene in humans. Functionally, this protein is a known subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. The canonical protein structure is reported to have an amino acid length of 631 residues, a mass of 69.3 kDa, and is a member of the SWP1 protein family. It is known to be localized in the ER and is reported to be expressed in all tissues tested. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. Other alias names for this target include RPN-II, RPNII, SWP1, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, and RIBIIR.
The detection range for different RPN2 ELISA kits can vary, with some assays measuring target concentrations as low as 78 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.