FGFR4 ELISA kits are immunoassay tools for the measurement of the protein fibroblast growth factor receptor 4, which is encoded by the FGFR4 gene in humans. Functionally, this protein is reported to be a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. The canonical protein structure is reported to have an amino acid length of 802 residues, a mass of 88 kDa, and is a member of the Tyr protein kinase protein family. It is known to be localized in the ER and cell membrane and is reported to be expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated, ubiquitinated and phosphorylated. Other alias names for this target include JTK2, TKF, hydroxyaryl-protein kinase, protein-tyrosine kinase, tyrosine kinase related to fibroblast growth factor receptor, and CD334.
Some FGFR4 ELISA kits can detect targets at levels as low as 12.5 pg/mL and as high as 400 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.