The following Endothelin 3 ELISA kits are useful research tools for the measurement of endothelin 3 in biological samples. In humans this protein is encoded by the EDN3 gene. This protein has been described to function in axon guidance and cell proliferation. The canonical protein structure is reported to have an amino acid length of 238 residues, a mass of 25.5 kDa, and is a member of the Endothelin/sarafotoxin protein family. It has been described to be a secreted protein. In addition, it is reported to be expressed in trophoblasts and placental stem villi vessels, but not in cultured placental smooth muscle cells. As many as 3 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Hirschsprung disease. This protein may also be known as ET3, HSCR4, PPET3, WS4B, preproendothelin-3, and ET-3.
The detection range for different endothelin 3 ELISA kits can vary, with some assays measuring target concentrations as low as 0.5 ng/L and as high as 400 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.