IARS1 ELISA kits are immunoassay tools for the measurement of the protein isoleucyl-tRNA synthetase 1, which is encoded by the IARS1 gene in humans. Functionally, this protein is known to catalyze the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. The canonical protein structure is reported to have an amino acid length of 1262 residues, a mass of 144.5 kDa, and is a member of the Class-I aminoacyl-tRNA synthetase protein family. It is known to be localized in the cytoplasm and is reported to be expressed in liver and muscle. The IARS1 gene has been associated with the disease, Growth retardation, impaired intellectual development, hypotonia, and hepatopathy. Other alias names for this target include IARS, ILERS, ILRS, IRS, PRO0785, and GRIDHH.
The detection range for different IARS1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.31 ng/mL and as high as 40 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.