SMG1 ELISA kits are immunoassay tools for the measurement of the protein SMG1 nonsense mediated mRNA decay associated PI3K related kinase, which is encoded by the SMG1 gene in humans. Functionally, this protein is a serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. The canonical protein structure is reported to have an amino acid length of 3661 residues, a mass of 410.5 kDa, and is a member of the PI3/PI4-kinase protein family. It is known to be localized in the nucleus and cytoplasm and is found to be widely expressed, with highest level in heart and skeletal muscle. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. Other alias names for this target include ATX, serine/threonine-protein kinase SMG1, PI-3-kinase-related kinase SMG-1, and 61E3.4.
The detection range for different SMG1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.78 ng/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.