LEO1 ELISA kits are immunoassay tools for the measurement of the protein LEO1 homolog, Paf1/RNA polymerase II complex component, which is encoded by the LEO1 gene in humans. Functionally, this protein is a known component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. The canonical protein structure is reported to have an amino acid length of 666 residues, a mass of 75.4 kDa, and is a member of the LEO1 protein family. It is known to be localized in the nucleus and is reported to be highly expressed in skeletal muscle and heart. As many as 2 protein isoforms have been reported. The LEO1 gene has been associated with the disease, . Other alias names for this target include Leo1 Paf1/RNA polymerase II complex component, Leo1, Paf1/RNA polymerase II complex component, homolog, replicative senescence down-regulated leo1-like protein, and RNA polymerase-associated protein LEO1.
The detection range for different Leo1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.313 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.