GANAB ELISA kits are immunoassay tools for the measurement of the protein glucosidase II alpha subunit, which is encoded by the GANAB gene in humans. Functionally, this protein is a known catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. The canonical protein structure is reported to have an amino acid length of 944 residues, a mass of 106.9 kDa, and is a member of the Glycosyl hydrolase 31 protein family. It is known to be localized in the ER and golgi and is notably expressed in placenta. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The GANAB gene has been associated with the disease, Polycystic kidney disease 3 with or without polycystic liver disease. Other alias names for this target include GIIA, GLUII, PKD3, neutral alpha-glucosidase AB, alpha-glucosidase 2, and G2AN.
Some GANAB ELISA kits can detect targets at levels as low as 3 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.