The following ryanodine receptor 2 ELISA kits are useful research tools for the measurement of ryanodine receptor 2 in biological samples. In humans this protein is encoded by the RYR2 gene. This protein is reported to be a calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. The canonical protein structure is reported to have an amino acid length of 4967 residues, a mass of 564.6 kDa, and is a member of the Ryanodine receptor (TC 1.A.3.1) protein family. It is notably expressed in heart muscle. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated. The gene encoding this protein has been associated with the disease, Arrhythmogenic right ventricular dysplasia. This protein may also be known as ARVD2, RyR, VACRDS, VTSIP, cardiac muscle ryanodine receptor-calcium release channel, and ARVC2.
The detection range for different ryanodine receptor 2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.05 ng/mL and as high as 40 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.