DONSON ELISA kits are immunoassay tools for the measurement of the protein DNA replication fork stabilization factor DONSON, which is encoded by the DONSON gene in humans. Functionally, this protein is reported to be a replisome component that maintains genome stability by protecting stalled or damaged replication forks. The canonical protein structure is reported to have an amino acid length of 566 residues, a mass of 62.7 kDa, and is a member of the DONSON protein family. It is known to be localized in the nucleus and is reported to be expressed in the brain, with higher levels in prenatal compared to adult brain. As many as 3 protein isoforms have been reported. The DONSON gene has been associated with the disease, Microcephaly-micromelia syndrome. Other alias names for this target include C21orf60, MIMIS, MISSLA, protein downstream neighbor of Son, downstream neighbor of SON, and B17.
Some Donson ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.