TOP3A ELISA kits are immunoassay tools for the measurement of the protein DNA topoisomerase III alpha, which is encoded by the TOP3A gene in humans. Functionally, this protein is known to be involved in DNA repair. The canonical protein structure is reported to have an amino acid length of 1001 residues, a mass of 112.4 kDa, and is a member of the Type IA topoisomerase protein family. It is known to be localized in the mitochondria. As many as 3 protein isoforms have been reported. The TOP3A gene has been associated with the disease, Microcephaly, growth restriction, and increased sister chromatid exchange. Other alias names for this target include PEOB5, TOP3, ZGRF7, DNA topoisomerase 3-alpha, topo III-alpha, and MGRISCE2.
Some TOP3A ELISA kits can detect targets at levels as low as 0.15 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.