MAEA ELISA kits are immunoassay tools for the measurement of the protein macrophage erythroblast attacher, E3 ubiquitin ligase, which is encoded by the MAEA gene in humans. Functionally, this protein is an important component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. The canonical protein structure is reported to have an amino acid sequence of 396 residues and a mass of 45.3 kDa. It is known to be localized in the cell membrane, nucleus, and cytoplasm. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated. Other alias names for this target include EMP, GID9, HLC-10, P44EMLP, PIG5, and EMLP.
The detection range for different MAEA ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.