RUNX2 ELISA kits are immunoassay tools for the measurement of the protein RUNX family transcription factor 2, which is encoded by the RUNX2 gene in humans. Functionally, this protein is a reported transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. The canonical protein structure is reported to have an amino acid sequence of 521 residues and a mass of 56.6 kDa. It is known to be localized in the nucleus and is notably expressed in osteoblasts. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The RUNX2 gene has been associated with the disease, Cleidocranial dysplasia. Other alias names for this target include CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, and AML3.
Some RUNX2 ELISA kits can detect targets at levels as low as 31.25 pg/mL and as high as 400 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.