ATXN1 ELISA kits are immunoassay tools for the measurement of the protein ataxin 1, which is encoded by the ATXN1 gene in humans. Functionally, this protein is reported to be a chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. The canonical protein structure is reported to have an amino acid length of 815 residues, a mass of 86.9 kDa, and is a member of the ATXN1 protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be widely expressed throughout the body. The protein has been noted to be post-translationally ubiquitinated, sumoylated and phosphorylated. The ATXN1 gene has been associated with the disease, Spinocerebellar ataxia. Other alias names for this target include D6S504E, SCA1, alternative ataxin1, spinocerebellar ataxia type 1 protein, and ATX1.
There are ATXN1 ELISA kits that can detect a target at concentrations as low as 7.813 pg/mL and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.