ALKBH8 ELISA kits are immunoassay tools for the measurement of the protein alkB homolog 8, tRNA methyltransferase, which is encoded by the ALKBH8 gene in humans. Functionally, this protein is known to catalyze the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. The canonical protein structure is reported to have an amino acid length of 664 residues, a mass of 75.2 kDa, and is a member of the AlkB protein family. It is known to be localized in the nucleus and cytoplasm and is found to be widely expressed, with highest expression in spleen, followed by pancreas and lung. As many as 4 protein isoforms have been reported. The ALKBH8 gene has been associated with the disease, Intellectual developmental disorder. Other alias names for this target include AlkB homologue 8, S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8, alkB, alkylation repair homolog 8, and alkylated DNA repair protein alkB homolog 8.
Some ALKBH8 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.