HPGD ELISA kits are immunoassay tools for the measurement of the protein 15-hydroxyprostaglandin dehydrogenase, which is encoded by the HPGD gene in humans. Functionally, this protein is known to catalyze the NAD-dependent dehydrogenation (oxidation) of a broad array of hydroxylated polyunsaturated fatty acids (mainly eicosanoids and docosanoids, including prostaglandins, lipoxins and resolvins), yielding their corresponding keto (oxo) metabolites. The canonical protein structure is reported to have an amino acid length of 266 residues, a mass of 29 kDa, and is a member of the Short-chain dehydrogenases/reductases (SDR) protein family. It is known to be localized in the cytoplasm and is notably expressed in colon epithelium. As many as 5 protein isoforms have been reported. The HPGD gene has been associated with the disease, Hypertrophic osteoarthropathy. Other alias names for this target include PGDH, PGDH1, PHOAR1, SDR36C1, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], and 15-PGDH.
Some HPGD ELISA kits can detect targets at levels as low as 15.6 pg/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.