TH ELISA kits are immunoassay tools for the measurement of the protein tyrosine hydroxylase, which is encoded by the TH gene in humans. Functionally, this protein is known to catalyze the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa), the rate-limiting step in the biosynthesis of cathecolamines, dopamine, noradrenaline, and adrenaline. The canonical protein structure is reported to have an amino acid length of 528 residues, a mass of 58.6 kDa, and is a member of the Biopterin-dependent aromatic amino acid hydroxylase protein family. It is known to be localized in the nucleus, cytoplasmic vesicles, and cytoplasm and is reported to be mainly expressed in the brain and adrenal glands. As many as 6 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The TH gene has been associated with the disease, Segawa syndrome autosomal recessive. Other alias names for this target include DYT5b, TYH, tyrosine 3-monooxygenase, dystonia 14, tyrosine 3-hydroxylase, and DYT14.
There are TH ELISA kits that can detect a target at concentrations as low as 13.7 pg/mL and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.