PKP2 ELISA kits are immunoassay tools for the measurement of the protein plakophilin 2, which is encoded by the PKP2 gene in humans. Functionally, this protein is reported to regulate focal adhesion turnover resulting in changes in focal adhesion size, cell adhesion and cell spreading, potentially via transcriptional modulation of beta-integrins. The canonical protein structure is reported to have an amino acid length of 881 residues, a mass of 97.4 kDa, and is a member of the Beta-catenin protein family. It is known to be localized in the nucleus and cytoplasm and is notably expressed in heart right ventricle. As many as 2 protein isoforms have been reported. The PKP2 gene has been associated with the disease, Arrhythmogenic right ventricular dysplasia. Other alias names for this target include ARVD9.
The detection range for different PKP2 ELISA kits can vary, with some assays measuring target concentrations as low as 10 ng/L and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.