CHUK ELISA kits are immunoassay tools for the measurement of the protein component of inhibitor of nuclear factor kappa B kinase complex, which is encoded by the CHUK gene in humans. Functionally, this protein is reported to be a serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. The canonical protein structure is reported to have an amino acid length of 745 residues, a mass of 84.6 kDa, and is a member of the Ser/Thr protein kinase protein family. It is known to be localized in the nucleus and cytoplasm and is widely expressed across many tissue types. The protein has been noted to be post-translationally ubiquitinated, acetylated and phosphorylated. The CHUK gene has been associated with the disease, Cocoon syndrome. Other alias names for this target include IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16, inhibitor of nuclear factor kappa-B kinase subunit alpha, and BPS2.
The detection range for different CHUK ELISA kits can vary, with some assays measuring target concentrations as low as 3.12 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.