ATXN2 ELISA kits are immunoassay tools for the measurement of the protein ataxin 2, which is encoded by the ATXN2 gene in humans. Functionally, this protein is known to be involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. The canonical protein structure is reported to have an amino acid length of 1313 residues, a mass of 140.3 kDa, and is a member of the Ataxin-2 protein family. It is known to be localized in the cytoplasm and is reported to be expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. As many as 5 protein isoforms have been reported. The ATXN2 gene has been associated with the disease, Spinocerebellar ataxia. Other alias names for this target include SCA2, TNRC13, spinocerebellar ataxia type 2 protein, trinucleotide repeat-containing gene 13 protein, and ATX2.
There are ATXN2 ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.