AARS1 ELISA kits are immunoassay tools for the measurement of the protein alanyl-tRNA synthetase 1, which is encoded by the AARS1 gene in humans. Functionally, this protein is known to catalyze the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). The canonical protein structure is reported to have an amino acid length of 968 residues, a mass of 106.8 kDa, and is a member of the Class-II aminoacyl-tRNA synthetase protein family. It is known to be localized in the cytoplasm. As many as 2 protein isoforms have been reported. The AARS1 gene has been associated with the disease, Charcot-Marie-Tooth disease. Other alias names for this target include CMT2N, DEE29, EIEE29, HDLS2, TTD8, alanine--tRNA ligase, cytoplasmic, alaRS, and AARS.
Some AARS1 ELISA kits can detect targets at levels as low as 0.15 ng/mL and as high as 1000 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.