The following SRY-box transcription factor 18 ELISA kits are useful research tools for the measurement of SRY-box transcription factor 18 in biological samples. In humans this protein is encoded by the SOX18 gene. This protein is reported to be a transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis. The canonical protein structure is reported to have an amino acid sequence of 384 residues and a mass of 40.9 kDa. Its subcellular location is known to be in the nucleus. In addition, it is notably expressed in fetal lung, placenta, skeletal muscle, liver, kidney, spleen, prostate, ovary, msosmall intestine and colon. The gene encoding this protein has been associated with the disease, Hypotrichosis-lymphedema-telangiectasia syndrome. This protein may also be known as HLTS, transcription factor SOX-18, SRY (sex determining region Y)-box 18, SRY-box 18, and HLTRS.
The detection range for different SRY-box transcription factor 18 ELISA kits can vary, with some assays measuring target concentrations as low as 7 ng/L and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.