The GITR ELISA kits listed below are analytical tools for measuring concentrations of GITR in various samples. GITR is an alternative name for the human TNFRSF18 gene, which encodes the protein, TNF receptor superfamily member 18. It has been mentioned that GITR plays a role in the apoptotic pathway, among other functions. Structurally, the TNFRSF18 protein is 241 amino acid residues in length and 26 kilodaltons in mass. However, as many as 3 protein isoforms have been identified. Its subcellular localization is in the cell membrane and is secreted. In terms of tissue specificity, it is reported to be expressed in lymph node, peripheral blood leukocytes and weakly in spleen. This protein is known to be glycosylated. Other names for this target antigen include AITR, CD357, and ENERGEN.
There are GITR ELISA kits that can detect a target at concentrations as low as 13.7 pg/mL and as high as 10 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.