GARS1 ELISA kits are immunoassay tools for the measurement of the protein glycyl-tRNA synthetase 1, which is encoded by the GARS1 gene in humans. Functionally, this protein is known to catalyze the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). The canonical protein structure is reported to have an amino acid length of 739 residues, a mass of 83.2 kDa, and is a member of the Class-II aminoacyl-tRNA synthetase protein family. It is known to be localized in the cytoplasm and is secreted and is reported to be widely expressed including in the brain and spinal cord. The GARS1 gene has been associated with the disease, Charcot-Marie-Tooth disease. Other alias names for this target include DSMAV, GARS, GlyRS, HMN5, HMN5A, SMAD1, SMAJI, and CMT2D.
The detection range for different GARS1 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 60 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.