RORA ELISA kits are immunoassay tools for the measurement of the protein RAR related orphan receptor A, which is encoded by the RORA gene in humans. Functionally, this protein is reported to be a nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. The canonical protein structure is reported to have an amino acid length of 523 residues, a mass of 59 kDa, and is a member of the Nuclear hormone receptor protein family. It is known to be localized in the nucleus and is found to be widely expressed in a number of tissues. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally methylated, ubiquitinated, sumoylated and phosphorylated. The RORA gene has been associated with the disease, Intellectual developmental disorder with or without epilepsy or cerebellar ataxia. Other alias names for this target include NR1F1, ROR1, ROR2, ROR3, RORa1, RORalpha, RZR-ALPHA, and IDDECA.
The detection range for different RORA ELISA kits can vary, with some assays measuring target concentrations as low as 10 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.