SMAD3 ELISA kits are immunoassay tools for the measurement of the protein SMAD family member 3, which is encoded by the SMAD3 gene in humans. Functionally, this protein is a known receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. The canonical protein structure is reported to have an amino acid length of 425 residues, a mass of 48.1 kDa, and is a member of the Dwarfin/SMAD protein family. It is known to be localized in the nucleus and cytoplasm. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated, acetylated and phosphorylated. The SMAD3 gene has been associated with the disease, Colorectal cancer. Other alias names for this target include HsT17436, JV15-2, LDS1C, LDS3, MADH3, hMAD-3, hSMAD3, and HSPC193.
There are SMAD3 ELISA kits that can detect a target at concentrations as low as 21.01 ng/L and as high as 500 µg/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.