SPG11 ELISA kits are immunoassay tools for the measurement of the protein SPG11 vesicle trafficking associated, spatacsin, which is encoded by the SPG11 gene in humans. Functionally, this protein is believed to play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport. The canonical protein structure is reported to have an amino acid sequence of 2443 residues and a mass of 278.9 kDa. It is known to be localized in the nucleus and cytoplasm and is reported to be expressed in all structures of brain, with a high expression in cerebellum. As many as 3 protein isoforms have been reported. The SPG11 gene has been associated with the disease, Spastic paraplegia. Other alias names for this target include SPG11, spatacsin vesicle trafficking associated, amyotrophic lateral sclerosis 5, colorectal carcinoma-associated protein, spastic paraplegia 11 (autosomal recessive), and spatacsin. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.