FGFR1 ELISA kits are immunoassay tools for the measurement of the protein fibroblast growth factor receptor 1, which is encoded by the FGFR1 gene in humans. Functionally, this protein is reported to be a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. The canonical protein structure is reported to have an amino acid length of 822 residues, a mass of 91.9 kDa, and is a member of the Tyr protein kinase protein family. It is known to be localized in the cell membrane, nucleus, cytoplasmic vesicles, and cytoplasm and is notably expressed in astrocytoma, neuroblastoma and adrenal cortex cell lines. As many as 21 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated, ubiquitinated and phosphorylated. The FGFR1 gene has been associated with the disease, Pfeiffer syndrome. Other alias names for this target include CD331, CEK, ECCL, FGFBR, FLG, FLT-2, FLT2, and BFGFR.
There are FGFR1 ELISA kits that can detect a target at concentrations as low as 31.2 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.