SPG7 ELISA kits are immunoassay tools for the measurement of the protein SPG7 matrix AAA peptidase subunit, paraplegin, which is encoded by the SPG7 gene in humans. Functionally, this protein is known to be involved in nervous system development and proteolysis. The canonical protein structure is reported to have an amino acid length of 795 residues, a mass of 88.2 kDa, and is a member of the AAA ATPase protein family; Peptidase M41 protein family. It is known to be localized in the mitochondria and is ubiquitously expressed across many tissue types. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally cleaved. The SPG7 gene has been associated with the disease, Spastic paraplegia. Other alias names for this target include CMAR, PGN, SPG5C, paraplegin, SPG7, paraplegin matrix AAA peptidase subunit, and CAR.
There are SPG7 ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.