SPOP ELISA kits are immunoassay tools for the measurement of the protein speckle type BTB/POZ protein, which is encoded by the SPOP gene in humans. Functionally, this protein is a known component of the cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. The canonical protein structure is reported to have an amino acid length of 374 residues, a mass of 42.1 kDa, and is a member of the Tdpoz protein family. It is known to be localized in the nucleus and is widely expressed across many tissue types. The SPOP gene has been associated with the disease, Nabais Sa-de Vries syndrome. Other alias names for this target include NEDMACE, NEDMIDF, NSDVS1, NSDVS2, TEF2, speckle-type POZ protein, HIB homolog 1, and BTBD32.
Some SPOP ELISA kits can detect targets at levels as low as 31.25 pg/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.