Anti-HYAL1 antibodies are used in the immunodetection of the protein hyaluronidase 1. In humans, the canonical protein has a reported length of 435 amino acid residues and a mass of 48.4 kDa. Its subcellular localization is in the lysosomes and is secreted. Up to 7 different isoforms have been reported for this protein. It is reported to be highly expressed in the liver, kidney and heart. A member of the Glycosyl hydrolase 56 protein family, HYAL1 is suspected to have a role in promoting tumor progression. Post-translational modifications have been described, including glycosylation. The HYAL1 gene has been associated with the disease, Mucopolysaccharidosis. Synonyms for this target antigen include MPS9, NAT6, hyaluronoglucosaminidase 1, luCa-1, lung carcinoma protein 1, and LUCA1. HYAL1 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. A number of HYAL1 antibodies have been mentioned in research publications and have associated citations. Western Blot and Immunohistochemistry are common applications for these antibodies.