Anti-ASB14 antibodies are used in the immunodetection of the protein ankyrin repeat and SOCS box containing 14. In humans, the canonical protein has a reported length of 587 amino acid residues and a mass of 65.3 kDa. Up to 3 different isoforms have been reported for this protein. A member of the Ankyrin SOCS box (ASB) protein family, ASB14 is believed to be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Synonyms for this target antigen include ankyrin repeat and SOCS box protein 14 and ankyrin repeat domain-containing SOCS box protein Asb-14. ASB14 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Western Blot is the most common application for the ASB14 antibodies listed below. ELISA and Immunohistochemistry are also common applications.