Anti-HSULF-1 antibodies enable researchers to detect and measure the HSULF-1 antigen in biological samples. This target is a reported synonym of the SULF1 gene, which encodes sulfatase 1. This protein is known to function in the apoptotic pathway and bone development, among other biological roles. The human version of HSULF-1 has a canonical amino acid length of 871 residues and a protein mass of 101 kilodaltons. It is reported to be localized in the ER, Golgi, and is secreted of cells and notably expressed in many tissues, such as the appendix and nasopharynx. HSULF-1 is a member of the Sulfatase protein family.