Anti-b(2)gcn antibodies are used in antigen-specific immunodetection in biological samples. The target b(2)gcn is a known alias name of the protein eukaryotic translation initiation factor 6, encoded by the EIF6 gene in humans. This 245-amino acid residue protein is known to bind to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. It is localized to the nucleus and cytoplasm of the cell and features phosphorylated post-translational modifications. In terms of tissue expression, it is noted to be expressed at very high levels in colon carcinoma with lower levels in normal colon and ileum and lowest levels in the kidney and muscle. Other synonyms for b(2)gcn include CAB, EIF3A, and ITGB4BP.