Anti-SPHKAP antibodies are used in the immunodetection of the protein SPHK1 interactor, AKAP domain containing. In humans, the canonical protein has a reported length of 1700 amino acid residues and a mass of 186.5 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the heart. A member of the AKAP110 protein family, Sphkap is reported to be an anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. Synonyms for this target antigen include A-kinase anchor protein SPHKAP, SPHK1 (sphingosine kinase type 1) interacting protein, SPHK1-interactor and AKAP domain-containing protein, sphingosine kinase type 1-interacting protein, and SKIP. SPHKAP gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some Sphkap antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunocytochemistry and Immunofluorescence are also common applications.