Anti-TMEM131L antibodies are used in the immunodetection of the protein transmembrane 131 like. In humans, the canonical protein has a reported length of 1609 amino acid residues and a mass of 179.3 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 5 different isoforms have been reported for this protein. It is reported to be expressed in thymocytes. A member of the TMEM131 protein family, TMEM131L is reported to be a membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include KIAA0922 and transmembrane protein 131-like. TMEM131L gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. ELISA is the most common application for the TMEM131L antibodies listed below. Flow Cytometry and Western Blot are also common applications.