Anti-SKA3 antibodies are used in the immunodetection of the protein spindle and kinetochore associated complex subunit 3. In humans, the canonical protein has a reported length of 412 amino acid residues and a mass of 46.4 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of a the SKA3 protein family, SKA3 is a known component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Synonyms for this target antigen include spindle and kinetochore-associated protein 3.