Anti-SH2B2 antibodies are used in the immunodetection of the protein SH2B adaptor protein 2. In humans, the canonical protein has a reported length of 632 amino acid residues and a mass of 67.7 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in spleen, prostate, testis, uterus, small intestine and skeletal muscle. A member of the SH2B adapter protein family, SH2B2 is known to be involved with cytoskeleton organization and brown fat cell differentiation. Synonyms for this target antigen include SH2B adapter protein 2, SH2 and PH domain-containing adapter protein APS, adapter protein with pleckstrin homology and Src homology 2 domains, and APS. SH2B2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some SH2B2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.