Anti-Ubiquilin 2 antibodies are used in the immunodetection of the protein encoded by the UBQLN2 gene. In humans, the canonical protein has a reported length of 624 amino acid residues and a mass of 65.7 kDa. Its subcellular localization is in the nucleus, cytoplasmic vesicles, and cytoplasm. It is known to play an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin-proteasome system (UPS), autophagy and the endoplasmic reticulum-associated protein degradation (ERAD) pathway. Other names for this target antigen include CHAP1, DSK2, HRIHFB2157, N4BP4, PLIC2, Nedd4 binding protein 4, protein linking IAP with cytoskeleton 2, and ALS15.