Anti-TMEM123 antibodies are used in the immunodetection of the protein transmembrane protein 123. In humans, the canonical protein has a reported length of 208 amino acid residues and a mass of 21.5 kDa. Its subcellular localization is in the membrane. Up to 2 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the CD164 protein family, TMEM123 is known to be implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include KCT-3, keratinocytes associated transmembrane protein 3, pro-oncosis receptor inducing membrane injury, serine/threonine-rich receptor, and porimin. TMEM123 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some TMEM123 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Flow Cytometry is also a common application.