Anti-VAMP (vesicle-associated membrane protein)-associated protein B and C antibodies are used in antigen-specific immunodetection in biological samples. The target VAMP (vesicle-associated membrane protein)-associated protein B and C is a known alias name of the protein VAMP associated protein B and C, encoded by the VAPB gene in humans. This 243-amino acid residue protein is known to participate in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. It is localized to the ER of the cell. In terms of tissue expression, it is ubiquitously expressed across many tissue types. Other synonyms for VAMP (vesicle-associated membrane protein)-associated protein B and C include ALS8, ALS8, and VAMP-B.