Anti-DVL1 antibodies are used in the immunodetection of the protein dishevelled segment polarity protein 1. In humans, the canonical protein has a reported length of 695 amino acid residues and a mass of 75.2 kDa. Its subcellular localization is in the cell membrane, cytoplasmic vesicles, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the DSH protein family, DVL1 is reported to participate in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Synonyms for this target antigen include DVL, DVL1L1, DVL1P1, segment polarity protein dishevelled homolog DVL-1, DSH homolog 1, and DRS2. DVL1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 60 citations in the literature describe the use of DVL1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.