Anti-EIF3A antibodies are used in the immunodetection of the protein eukaryotic translation initiation factor 3 subunit A. In humans, the canonical protein has a reported length of 1382 amino acid residues and a mass of 166.6 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of a the EIF-3 subunit A protein family, EIF3A is reported to be a RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185, and EIF3.