Anti-COX5B antibodies are used in the immunodetection of the protein cytochrome c oxidase subunit 5B. In humans, the canonical protein has a reported length of 129 amino acid residues and a mass of 13.7 kDa. Its subcellular localization is in the mitochondria. It is notably widely expressed in many tissue types. A member of the Cytochrome c oxidase subunit 5B protein family, COX5B is a known component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. Synonyms for this target antigen include cytochrome c oxidase subunit 5B, mitochondrial, cytochrome c oxidase polypeptide VB, mitochondrial, cytochrome c oxidase subunit Vb, epididymis secretory sperm binding protein, and COXVB. COX5B gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of COX5B antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.