Anti-EPB41L5 antibodies are used in the immunodetection of the protein erythrocyte membrane protein band 4.1 like 5. In humans, the canonical protein has a reported length of 733 amino acid residues and a mass of 81.9 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. EPB41L5 is reported to play a role in in the formation and organization of tight junctions during the establishment of polarity in epithelial cells. Synonyms for this target antigen include band 4.1-like protein 5 and yurt homolog.