Anti-CHRNE antibodies are used in the immunodetection of the protein cholinergic receptor nicotinic epsilon subunit. In humans, the canonical protein has a reported length of 493 amino acid residues and a mass of 54.7 kDa. Its subcellular localization is in the cell membrane. A member of the Ligand-gated ion channel (TC 1.A.9) protein family, CHRNE is known to be involved with chemical synaptic transmission and signal transduction pathways. Post-translational modifications have been described, including glycosylation. The CHRNE gene has been associated with the disease, Myasthenic syndrome. Synonyms for this target antigen include CMS1A1, CMS1D, CMS1E, CMS2A, CMS4A, CMS4B, CMS4C, and ACHRE. CHRNE gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. Some CHRNE antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.