Anti-Aquaporin 8 antibodies are used for the immunodetection of the protein encoded by the AQP8 gene. In humans, the canonical protein has a reported length of 261 amino acid residues and a mass of 27.4 kDa. Its subcellular localization is in the mitochondria, ER, and cell membrane. It is notably expressed in the sperm midpiece. A member of the MIP/aquaporin (TC 1.A.8) protein family, it is a reported channel that allows the facilitated permeation of water and uncharged molecules, such as hydrogen peroxide and the neutral form of ammonia (NH3), through cellular membranes such as plasma membrane, inner mitochondrial membrane and endoplasmic reticulum membrane of several tissues. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of Aquaporin 8 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.